Comparative deposition of inhaled aerosols in experimental animals and humans: a review.

نویسنده

  • R B Schlesinger
چکیده

The biological effects of inhaled aerosols are often related to their site(s) of deposition within the respiratory tract. However, deposition patterns may differ between humans and those experimental animals commonly used in inhalation toxicology studies, making cross-species risk extrapolations difficult. This paper reviews the factors that control deposition and synthesizes much of the available data on comparative regional deposition.

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عنوان ژورنال:
  • Journal of toxicology and environmental health

دوره 15 2  شماره 

صفحات  -

تاریخ انتشار 1985